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1

The KEEPER™ trial: levetiracetam adjunctive treatment of partial-onset seizures in an open-label community-based study

M.J Morrell, I Leppik, J French, J Ferrendelli, J Han, L Magnus

Journal:

Epilepsy Research

Year:

2003

Language:

english

File:

PDF, 131 KB

english, 2003

2

ChemInform Abstract: Synthesis and Anticonvulsant Activities of 3,3-Dialkyl- and 3-Alkyl-3- benzyl-2-piperidinones (δ-Valerolactams) and Hexahydro-2H-azepin- 2-ones (.epsilon.-Caprolactams).

P. A. REDDY, K. E. WOODWARD, S. M. MCILHERAN, B. C. H. HSIANG, T. N. LATIFI, M. W. HILL, S. M. ROTHMAN, J. A. FERRENDELLI, D. F. COVEY

Journal:

Year:

1997

File:

PDF, 32 KB

1997

3

Adenylate Cyclases in Vertebrate Retina: Enzymatic Characteristics in Normal and Dystrophic Mouse Retina

J. A. Ferrendelli, K. M. Campau, G. W. De Vries

Journal:

Journal of Neurochemistry

Year:

1982

Language:

english

File:

PDF, 548 KB

english, 1982

4

Adenylate Cyclases in the Vertebrate Retina: Distribution and Characteristics in Rabbit and Ground Squirrel

G. W. De Vries, K. M. Campau, J. A. Ferrendelli

Journal:

Journal of Neurochemistry

Year:

1982

Language:

english

File:

PDF, 601 KB

english, 1982

5

Chronic ketosis and cerebral metabolism

Dr. Darryl C. Devivo, Mary P. Leckie, James S. Ferrendelli, David B. McDougal Jr

Journal:

Annals of Neurology

Year:

1978

Language:

english

File:

PDF, 644 KB

english, 1978

6

Inhibitory effects of anticonvulsant drugs on cyclic nucleotide accumulation in brain

Dr James A. Ferrendelli, Dorothy A. Kinscherf

Journal:

Annals of Neurology

Year:

1979

Language:

english

File:

PDF, 527 KB

english, 1979

7

Two affinity states of M1 muscarine receptors

Lincoln T. Potter, Cynthia A. Ferrendelli, Helene E. Hanchett

Journal:

Cellular and Molecular Neurobiology

Year:

1988

Language:

english

File:

PDF, 585 KB

english, 1988

8

The central medial nucleus: thalamic site of seizure regulation

John W. Miller, James A. Ferrendelli

Journal:

Year:

1990

Language:

english

File:

PDF, 926 KB

english, 1990

9

Alkyl-substituted γ-butyrolactones act at a distinct site allosterically linked to the TBPS/picrotoxinin site on the GABAA receptor complex

Katherine D. Holland, Michael G. Bouley, Douglas F. Covey, James A. Ferrendelli

Journal:

Year:

1993

Language:

english

File:

PDF, 423 KB

english, 1993

10

Rational Polypharmacy

James A. Ferrendelli

Journal:

Year:

1995

Language:

english

File:

PDF, 405 KB

english, 1995

11

Letter: Quantitative localization of cyclic nucleotides in cerebellar folia.

Rubin, E. H., Ferrendelli, J. A.

Journal:

Journal of Histochemistry & Cytochemistry

Year:

1976

Language:

english

File:

PDF, 437 KB

english, 1976

12

Regional cortical metabolism in focal ischemia

Ratcheson, Robert A., Ferrendelli, James A.

Journal:

Journal of Neurosurgery

Year:

1980

Language:

english

File:

PDF, 1.38 MB

english, 1980

13

Use of Nonradioactive 2-Deoxyglucose to Study Compartmentation of Brain Glucose Metabolism and Rapid Regional Changes in Rate

David B. McDougal, Jr., James A. Ferrendelli, Vera Yip, Mary Ellen Pusateri, Joyce G. Carter, Maggie M.-Y. Chi, Beverly Norris, Jill Manchester and Oliver H. Lowry

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.02 MB

english, 1990

14

Effect of nitrous oxide anesthesia upon cerebral energy metabolism

R. A. Ratcheson, L. Bilezikjian, J. A. Ferrendelli

Journal:

Journal of Neurochemistry

Year:

1977

Language:

english

File:

PDF, 263 KB

english, 1977

15

Alkyl-substituted γ-butyrolactones as potential tools in the study and treatment of epilepsy

William E. Klunk, Douglas F. Covey, James A. Ferrendelli

Journal:

Biochemical Pharmacology

Year:

1983

Language:

english

File:

PDF, 691 KB

english, 1983

16

Application of Imidazole as a Selective Inhibitor of Thromboxane Synthetase in Human Platelets

Philip Needleman, Amiram Raz, James A. Ferrendelli and Mark Minkes

Journal:

Proceedings of the National Academy of Sciences

Year:

1977

Language:

english

File:

PDF, 1.23 MB

english, 1977

17

Mechanism of Action of Nerve Growth Factor and Cyclic AMP on Neurite Outgrowth in Embryonic Chick Sensory Ganglia: Demonstration of Independent Pathways of Stimulation

William A. Frazier, Cathleen Earhart Ohlendorf, Linda Forrest Boyd, Luigi Aloe, Eugene M. Johnson, James A. Ferrendelli and Ralph A. Bradshaw

Journal:

Proceedings of the National Academy of Sciences

Year:

1973

Language:

english

File:

PDF, 1.37 MB

english, 1973

18

Lennox-gastaut syndrome and positron emission tomography

James A. Ferrendelli

Journal:

Annals of Neurology

Year:

1987

Language:

english

File:

PDF, 122 KB

english, 1987

19

QUICK FREEZING OF THE MURINE CNS: COMPARISON OF REGIONAL COOLING RATES AND METABOLITE LEVELS WHEN USING LIQUJD NITROGEN OR FREON-12

J. A. Ferrendelli, M. H. Gay, W. G. Sedgwick, M. M. Chang

Journal:

Journal of Neurochemistry

Year:

1972

Language:

english

File:

PDF, 594 KB

english, 1972

20

Neurotransmitters, seizures and epilepsy: Edited by P. L. Morselli, K. G. Lloyd, W. Loscher, B. Meldrum, and E. H. Reynolds New York, Raven Press, 1981 378 pp., $42.00

James A. Ferrendelli

Journal:

Surgical Neurology

Year:

1982

Language:

english

File:

PDF, 102 KB

english, 1982

21

Physiological regulation of the picrotoxin receptor by gamma- butyrolactones and gamma-thiobutyrolactones in cultured hippocampal neurons

Holland, KD, Ferrendelli, JA, Covey, DF, Rothman, SM

Journal:

Journal of Neuroscience

Year:

1990

Language:

english

File:

PDF, 1.07 MB

english, 1990

22

Structure-activity studies of fluoroaljyl-substituted γ-butyrolactone and γ-thiobutyrolactone modulators of GABAA receptor function

Daniel J. Canney, Hwang-Fun Lu, Ann C. McKeon, Kong-Woo Yoon, Kun Xu, Katherine D. Holland, Steven M. Rothman, James A. Ferrendelli, Douglas F. Covey

Journal:

Bioorganic & Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 1.42 MB

english, 1998

23

Thromboxane synthetase inhibitors as pharmacological tools: Differential biochemical and biological effects on platelet suspensions

Philip Needleman, Bruce Bryan, Angela Wyche, Sue D. Bronson, Ken Eakins, James A. Ferrendelli, Mark Minkes

Journal:

Year:

1977

Language:

english

File:

PDF, 533 KB

english, 1977

24

Distribution of 3':5'-cyclic AMP and 3':5'-cyclic GMP in rabbit retina in vivo: selective effects of dark and light adaptation and ischemia.

Orr, H. T., Lowry, O. H., Cohen, A. I., Ferrendelli, J. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

1976

Language:

english

File:

PDF, 798 KB

english, 1976

25

Roles of biogenic amines and cyclic nucleotides in seizure mechanisms

Dr James A. Ferrendelli

Journal:

Annals of Neurology

Year:

1984

Language:

english

File:

PDF, 730 KB

english, 1984

26

Relationships between seizure activity and cyclic nucleotide levels in brain

James A. Ferrendelli, Ann C. Blank, Robert A. Gross

Journal:

Year:

1980

Language:

english

File:

PDF, 688 KB

english, 1980

27

The effect of oxotremorine and atropine on cGMP and cAMP levels in mouse cerebral cortex and cerebellum

J.A. Ferrendelli, A.L. Steiner, D.B. McDougal Jr., D.M. Kipnis

Journal:

Biochemical and Biophysical Research Communications

Year:

1970

Language:

english

File:

PDF, 348 KB

english, 1970

28

Adenosine-mediated regulation of cyclic AMP levels in isolated incubated retinas

Christine Blazynski, Dorothy A. Kinscherf, Katalin M. Geary, James A. Ferrendelli

Journal:

Year:

1986

Language:

english

File:

PDF, 487 KB

english, 1986

29

Pharmacology of Antiepileptic Drugs

Ferrendelli, James A.

Journal:

Year:

1987

Language:

english

File:

PDF, 264 KB

english, 1987

30

Synthesis and Anticonvulsant Activities of 3,3-Dialkyl- and 3-Alkyl-3-benzyl-2-piperidinones (δ-Valerolactams) and Hexahydro-2 H -azepin-2-ones (ε-Caprolactams)

Reddy, P. Amruta, Woodward, Karen E., McIlheran, Sarah M., Hsiang, Bonnie C. H., Latifi, Tammy N., Hill, Matthew W., Rothman, Steven M., Ferrendelli, James A., Covey, Douglas F.

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 241 KB

english, 1997

31

Triene prostaglandins: Prostacyclin and thromboxane biosynthesis and unique biological properties

Needleman, P., Raz, A., Minkes, M. S., Ferrendelli, J. A., Sprecher, H.

Journal:

Proceedings of the National Academy of Sciences

Year:

1979

Language:

english

File:

PDF, 1.35 MB

english, 1979

32

REGIONAL LEVELS OF GLUCOSE, AMINO ACIDS, HIGH ENERGY PHOSPHATES, AND CYCLIC NUCLEOTIDES IN THE CENTRAL NERVOUS SYSTEM DURING HYPOGLYCEMIC STUPOR AND BEHAVIORAL RECOVERY

J. M. Gorell, Pamela H. Dolkart, J. A. Ferrendelli

Journal:

Journal of Neurochemistry

Year:

1976

Language:

english

File:

PDF, 588 KB

english, 1976

33

Regionally Selective Metabolic Effects of Hypoglycemia in Brain

Robert A. Ratcheson, Ann C. Blank, James A. Ferrendelli

Journal:

Journal of Neurochemistry

Year:

1981

Language:

english

File:

PDF, 622 KB

english, 1981

34

Use of nonradioactive 2-deoxyglucose to study compartmentation of brain glucose metabolism and rapid regional changes in rate.

McDougal, D. B., Ferrendelli, J. A., Yip, V., Pusateri, M. E., Carter, J. G., Chi, M. M., Norris, B., Manchester, J., Lowry, O. H.

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.17 MB

english, 1990

35

Distribution of 3′:5′-cyclic AMP and 3′:5′-Cyclic GMP in Rabbit Retina in vivo: Selective Effects of Dark and Light Adaptation and Ischemia

Harry T. Orr, Oliver H. Lowry, Adolph I. Cohen and James A. Ferrendelli

Journal:

Proceedings of the National Academy of Sciences

Year:

1976

Language:

english

File:

PDF, 687 KB

english, 1976

36

THE EFFECT OF ELECTROSHOCK ON REGIONAL CNS ENERGY RESERVES IN MICE

J. A. Ferrendelli, D. B. McDougal Jr.

Journal:

Journal of Neurochemistry

Year:

1971

Language:

english

File:

PDF, 600 KB

english, 1971

37

INFLUENCE OF DIVALENT CATIONS ON REGULATION OF CYCLIC GMP AND CYCLIC AMP LEVELS IN BRAIN TISSUE

J. A. Ferrendelli, E. H. Rubin, Dorothy A. Kinscherf

Journal:

Journal of Neurochemistry

Year:

1976

Language:

english

File:

PDF, 740 KB

english, 1976

38

Triene Prostaglandins: Prostacyclin and Thromboxane Biosynthesis and Unique Biological Properties

Philip Needleman, Amiram Raz, Mark S. Minkes, James A. Ferrendelli and Howard Sprecher

Journal:

Proceedings of the National Academy of Sciences

Year:

1979

Language:

english

File:

PDF, 798 KB

english, 1979

39

beta-Adrenergic regulation of adenosine 3',5'-monophosphate concentration in brain microvessels

Herbst, T., Raichle, M., Ferrendelli, J.

Journal:

Year:

1979

Language:

english

File:

PDF, 779 KB

english, 1979

40

Electroencephalographic Effects of Intracisternally Injected Nonionic X-Ray Contrast Media in Rats

ADAMS, M. D., RALSTON, W. H., MILLER, J. W., FERRENDELLI, J. A.

Journal:

Investigative Radiology

Year:

1990

File:

PDF, 1.13 MB

1990

41

Interruption of the mammillothalamic tract prevents seizures in guinea pigs

Mirski, M., Ferrendelli, J.

Journal:

Year:

1984

Language:

english

File:

PDF, 964 KB

english, 1984

42

Measurement of cyclic nucleotides in histologically defined samples of brain and retina

J.A. Ferrendelli, E.H. Rubin, H.T. Orr, D.A. Kinscherf, O.H. Lowry

Journal:

Analytical Biochemistry

Year:

1977

Language:

english

File:

PDF, 495 KB

english, 1977

43

THE EFFECT OF AUDIOGENIC SEIZURES ON REGIONAL CNS ENERGY RESERVES, GLYCOLYSIS AND CITRIC ACID CYCLE FLUX

J. A. Ferrendelli, D. B. McDougal Jr

Journal:

Journal of Neurochemistry

Year:

1971

Language:

english

File:

PDF, 793 KB

english, 1971

44

Convulsant and anti-convulsant gammabutyrolactones bind at the picrotoxinin/t-butylbicyclophosphorothionate (TBPS) receptor

Jeffrey A. Levine, James A. Ferrendelli, Douglas F. Covey

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 277 KB

english, 1985

45

Effects of anticonvulsant and convulsant gamma-butyrolactones and thiobutyrolactones on gaba-mediated chloride uptake

Dean K. Naritoku, Jeffrey A. Levine, Douglas F. Covey, James A. Ferrendelli

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 343 KB

english, 1987

46

Physiological modulation of the GABA receptor by convulsant and anticonvulsant barbiturates in cultured rat hippocampal neurons

Katherine D. Holland, Daniel J. Canney, Steven M. Rothman, J.A. Ferrendelli, Douglas F. Covey

Journal:

Year:

1990

Language:

english

File:

PDF, 326 KB

english, 1990

47

Alkyl-substituted thiolo-, thiono-, and dithio-.gamma.-butyrolactones: new classes of convulsant and anticonvulsant agents

Levine, Jeffrey A., Ferrendelli, James A., Covey, Douglas F.

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 593 KB

english, 1986

48

Effect of anticonvulsant drugs on kainic acid-induced epileptiform activity

David B. Clifford, Eric W. Lothman, W.Edwin Dodson, James A. Ferrendelli

Journal:

Experimental Neurology

Year:

1982

Language:

english

File:

PDF, 685 KB

english, 1982

49

Developmental alteration in GABAA receptor structure and physiological properties in cultured cerebellar granule neurons

Mathews, Gregory C., Bolos-Sy, Annabel M., Holland, Katherine D., Isenberg, Keith E., Covey, Douglas F., Ferrendelli, James A., Rothman, Steven M.

Journal:

Year:

1994

Language:

english

File:

PDF, 1.61 MB

english, 1994

50

Lactone Modulation of the γ-Aminobutyric Acid A Receptor: Evidence for a Positive Modulatory Site

Williams, Korwyn L., Tucker, Joseph B., White, Geoffrey, Weiss, David S., Ferrendelli, James A., Covey, Douglas F., Krause, James E., Rothman, Steven M.

Journal:

Molecular Pharmacology

Year:

1997

Language:

english

File:

PDF, 353 KB

english, 1997

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